




| 101 | TOOLS FOR BIOMED ENGINEERING | 3 credits |
| Corequisite: 3450:149. Introduction to Biomedical Engineering. Personal computers, word processing, spreadsheets, mathematical computational software and computer aided drafting. | ||
| 111 | INTRO: BIOMEDICAL ENGR DESIGN | 3 credits |
| Prerequisites: 101 or permission. Students will be introduced to the interdisciplinary nature of Biomedical Engineering research and design through the use of lectures, discussions, homework and design projects. | ||
| 201 | BIOMED ENGR SOPHOMORE SEMINAR | 1 credits |
| Prerequisites: 101, sophomore standing or above. A seminar format to allow students to learn about current research and careers in Biomedical Engineering. Topics in technical communications will also be covered. | ||
| 210 | STATSTCL METHDS IN BIOMED ENGR | 3 credits |
| See department for course description. **Course not approved in EN-98-01 per department (12-05-05). | ||
| 220 | BIOMEDICAL COMPUTING | 3 credits |
| Prerequisites: 101, 3450:223. Programming in BASIC and Visual Basic for data acquisition, analysis and display. Object-oriented programming using biomedical engineering examples. High-level processing and display techniques using MATLAB. | ||
| 305 | INTRO: BIOPHYSICAL MEASUREMNTS | 4 credits |
| Prerequisites: 101 and 4400:231 or 4400:307. Corequisite: 3100:202. Biomedical Engineering involves measurement of Physiological processes in living organisms. An understanding of the variety of instruments used and the limitations are introduced. | ||
| 310 | MODEL & SIM OF BIOMED SYS | 3 credits |
| Prerequisite: 3450:335. Modeling and simulation of physiological systems and their interactions with therapeutic devices, such as the artificial kidney. | ||
| 325 | DESIGN OF MEDICAL DEVICES | 3 credits |
| Prerequisites: Junior/senior standing in the College of Engineering, the College of Polymer Science and Engineering or the College of Arts and Sciences. Design of Medical Devices, design criteria, human factors, patient care and monitoring devices, surgical devices, bench testing and legal liability. | ||
| 360 | BIOFLUID MECHANICS | 3 credits |
| Prerequisites: 3450:335, 3150:133, 3650:292, and 4600:203. Introduction to the fundamentals of fluid mechanics and their application to biological, cardiovascular, respiratory and other biofluid systems. | ||
| 365 | MECHANICS OF BIOLOG TISSUES | 3 credits |
| Prerequisites: 4300:202 and 3450:335. The mechanical properties of musculoskeletal tissues are presented along with modeling techniques and testing procedures. Tendons, ligaments, muscles, cartilage and bone will be addressed. | ||
| 370 | BIOMECH OF HUMAN MOVEMENT | 3 credits |
| Prerequisites: 3100:202 and 4600:203. The application of engineering mechanics and anatomy to study and analyze human movement. Lectures and in-class labs will introduce students to experimental and theoretical techniques. | ||
| 400 | BIOMATERIALS | 3 credits |
| Properties of Materials used in medicine and their interaction with biological materials will be discussed. Biocompatibility issues, material degradation, biomaterials testing will also be discussed. | ||
| 409 | INTRO: BIOMED ENGINEERING RSCH | 3 credits |
| Application of engineering principles to local area medical research. Includes biomaterials, orthopedics, artificial organs, biostereometrics, biometrics, biological signal and image analysis, biomechanics and computers in medicine. | ||
| 420 | BIOMD SIGNAL & IMAGE PROC | 3 credits |
| Prerequisites: 4400:163, 343. Introduction to the basic problems associated with biological signal and image processing applications, and appropriate approaches to dealing with them. | ||
| 422 | PHYSIOLOGICAL CONTROL SYSTEMS | 3 credits |
| Prerequisites: 3100:202, 3450:335. The basic techniques employed in control theory, systems analysis and model identification as they apply to physiological systems. | ||
| 430 | DESIGN OF MED IMAGING SYS | 3 credits |
| Prerequisites: 3100: 200, 3650:292, 4400:343,353, 4800:305, or permission of instructor. Physical principles and engineering design of medical imaging systems, with emphasis on digital radiography, computed tomography, nuclear medicine, ultrasound and magnetic resonance. | ||
| 435 | IMAGE SCIENCE | 3 credits |
| Prerequisites: 3100:200, 3650:292, 4400:343 or by permission of instructor. Principles of image science, image performance parameters and image assessment techniques of medical imaging systems, with emphasis on digital radiography, tomographic imaging, ultrasound and magnetic resonance. | ||
| 437 | PHYSICS OF MEDICAL IMAGING | 3 credits |
| Prerequisites: 3100:200, 3650:292, 4400:353, 4800:305. Physical principles of medical imaging modalities with emphasis on the properties, generation mechanisms and interaction of radiation with matter, physics of the image formation and optimization. | ||
| 440 | ADVANCED BIOMATERIALS | 3 credits |
| Prerequisite: 400. The interactions between biomaterials and medical devices will be analyzed with respect to their potential activiation of biological mechanisms. | ||
| 445 | EXP TECH - BIOMAT TISSUE ENGR | 3 credits |
| Prerequisite: 440. Laboratory experience that applies engineering concepts and practices to the analysis of biomaterials and tissue engineering. | ||
| 460 | EXPERMNTL TECH IN BIOMECHANICS | 3 credits |
| Prerequisites: 3150:153, 3450:335, 3650:292, 4600:203 or by permission of instructor. Principles of testing and measuring devices commonly used for biofluid and biosolid mechanics studies. Laboratories for demonstration and hands-on experience. | ||
| 470 | HUMAN FACTORS ENGINEERING | 3 credits |
| Reliability and human error, human capabilities and limitations, crew protection, display systems, controls and controlling actions, interface design principles, risk management, Safety and accident prevention. | ||
| 485 | ST: BIOMEDICAL ENGINEERING | 1-3 credits |
| Prerequisite: permission of advisor. Directed individual or group research or study in the student's field of interest. Topic subject to approval of advisor. | ||
| 491 | BIOMEDICAL ENGR DESIGN I | 2 credits |
| Prerequisite: 111. Corequisite: 305. The design process will be further discussed utilizing case studies and detailed biomedical engineering design projects. | ||
| 492 | BIOMEDICAL ENGR DESIGN II | 2 credits |
| Prerequisite: 491. The design process will be further discussed utilizing detailed biomedical engineering design projects. Projects will be required to be interdisciplinary in nature. | ||
| 522 | PHYSIOLOGICAL CONTROL SYSTEMS | 3 credits |
| Prerequisite: 3100:202 and 3450:335. The basic techniques employed in control theory, systems analysis, and model identification as they apply to physiological systems. | ||
| 530 | DESIGN OF MED IMAGING SYS | 3 credits |
| Prerequisites: 3100:200; 3650:292; 4400:343, 353; 4800:305; or by permission of instructor. Physical principles and engineering design of medical imaging systems, with emphasis on digital radiography, computed tomography, nuclear medicine, ultrasound and magnetic resonance. | ||
| 535 | IMAGE SCIENCE | 3 credits |
| Prerequisites: 3100:200, 3650:292, 4400:343, or by permission of the instructor. Principles of image science, image performance parameters and image assessment techniques of medical imaging systems, with emphasis on digital radiography, tomographic imaging, ultrasound and magnetic resonance. | ||
| 537 | PHYSICS OF MEDICAL IMAGING | 3 credits |
| Prerequisites: 3100:200, 3650:292, 4400:353, 4800:305. Physical principles of medical imaging modalities with emphasis on the properties, general mechanisms and interaction of radiation with matter, physics of the image formation and optimization. | ||
| 560 | EXPERMNTL TECH IN BIOMECHANICS | 3 credits |
| Prerequisites: 3150:153, 3450:335, 3650:292, 4600:203 or by permission. Principles of testing and measuring devices commonly used for biofluid and biosolid mechanics studies. Laboratories for demonstration and hands-on experience. | ||
| 570 | HUMAN FACTORS ENGINEERING | 3 credits |
| Reliability and human error, human capabilities and limitations, crew protection, display systems, controls and controlling actions, interface design principles, risk management, Safety and accident prevention. | ||
| 600 | BME GRADUATE COLLOQUIUM | 1 credits |
| (May be repeated for a maximum of 16 credits.) The Biomedical Engineering Colloquium is a seminar series designed to introduce students to current topics in biomedical engineering research, design and business. | ||
| 601 | BIOMEDICAL INSTRUMENTATION I | 4 credits |
| Prerequisites: 3100:561, 562, and 4400:232 or 4400:320. Clinical instrumentation to measure and display physiologic and anatomic parameters. Basic concepts of instrumentation including design criteria and operational analysis. Practical experience gained through the use of instrumented mammalian models. | ||
| 611 | BIOMETRY | 3 credits |
| Statistics and experimental design topics for the biomedical and biomedical engineering disciplines including: distributions, hypothesis testing and estimation, ANOVA, probit analysis and nonparametrics statistics. | ||
| 620 | NEURAL NETWORKS | 3 credits |
| Examination of highly parallel, distributed architectures for computing that are, to varying degrees, derived from structures observed in biological nervous systems. After an overview of how real neurons operate, the course will examine both lassial and modern neural computing architectures. Comparisons will be made with traditional serial machines and applications for which neural networks seem most promising will be examined. | ||
| 621 | SENSORY SYSTEMS ANALYSIS | 3 credits |
| Prerequisite: 4400:371 or equivalent, or by permission. Study of various sensory modalities from a systems engineering perspective. Techniques from linear and nonlinear systems analysis are applied to aspects of vision, hearing, touch, and position sensing in humans. Comparisons are made with artificial emulations of these senses. | ||
| 623 | PROC OF BIOMED SIGNALS | 3 credits |
| Prerequisites: graduate standing in the College of Engineering and 611 or equivalent. Concepts for the analysis of biological continuous signals and point processes including discriminant and principal component analysis, histograms, correlograms and data displays. | ||
| 624 | IMAGE PROC FOR BIOMEDICAL DATA | 3 credits |
| Image sampling, quantization, and transforms. Enhancements including smoothing and sharpening. Restoration using inverse and Wiener filters. Edge detection and thresholding with region growing for segmentation. | ||
| 627 | ADVANC-DRUG & GENE DELIVRY SYS | 3 credits |
| This course will examine technological innovations for the delivery of drugs and genes. Methods of introducing drugs and genes into the body, modeling drug transport, and metabolic responses of cells and organs will be analyzed. | ||
| 630 | BIOMEDICAL COMPUTING | 3 credits |
| Prerequisite: 4100:206 or equivalent. Computer applications in health care, clinical laboratories, AMHT, medical records, direct order entry, A-D, D-A conversion, patient monitoring, peripherals and interfaces, diagnostic algorithms, automated EEG, ECG systems. | ||
| 632 | DIAGNOSTIC IMAGING TECH | 3 credits |
| Advanced Diagnostic Imaging techniques as applied to Digital Radiography, Computed Tomography (CT), nuclear medicine, ultrasound imaging, magnetic resonance imaging (MRI), microwaves and optical confocal microscopy. | ||
| 633 | BIOMEDICAL OPTICS | 3 credits |
| Application of lightwave principles and optical fibers on the engineering design and development of instrumentation, techniques, and applications for medical diagnostic imaging, and treatment of disease. | ||
| 634 | MEDICAL IMAGING DEVICES | 3 credits |
| Imagining modalities including radiation, magnetic resonance, and sound. The formation of images. Specific devices including computer tomography, magnetic resonance, ultrasound, gamma cameras and PET. | ||
| 635 | BIOMEDICAL NANOTECHNOLOGY | 3 credits |
| Prerequisite: permission of instructor. Engineering principles of nanotechnology as applied to the design of instrumentation, systems and techniques, aimed to explore biomolecules and biomaterials at the microscopic level, at one billionth of a meter. | ||
| 640 | SPINE MECHANICS | 3 credits |
| Prerequisites: 3100:561 or equivalent; 4300:406 or equivalent; or permission. Physical properties and functional biomechanics of the spine. Kinematics and kinetics of the human spine. Biomechanics of scoliosis, trauma, instability, pain, and orthoses. Mechanics and design of surgical implants. | ||
| 641 | SOFT CONNCTVE TISSUE BIOMECHAN | 3 credits |
| Prerequisites: 3100:561 or equivalent; 4300:407 or equivalent; or permission. Physical properties and functional biomechanics of ligament, tendon, joint-capsule insertions, myotendinous junction, articular cartilage and meniscus. The mechanics of injury, repair, and replacement for accelerated repair and improved function. | ||
| 642 | HARD CONNCTVE TISSUE BIOMECHAN | 3 credits |
| Prerequisites: 3100:561 or equivalent; 4300:407 or equivalent; or permission. Physical properties and functional biomechanics of bone. The biology and mechanics of fracture and fracture healing. Mechanics of external and internal fixators. Total joint implants and reconstruction techniques. | ||
| 644 | MUSCLE MECHANICS&OPTIMIZATION | 3 credits |
| Prerequisite: Graduate standing in the College of Engineering or by permission. Human body joint kinetics, muscle mechanics and modelling. The principles of optimization as applied to muscle forces, along with muscle anatomy and physiology. | ||
| 645 | MECHANICS IN PHYSIOL & MEDCNE | 3 credits |
| Prerequisites: 4600:310 and 4300:202 or equivalent. Blood rheology, mechanics of microcirculation, finite deformation theory, soft tissue mechanics, mechanics of blood and lymph circulation, kinetics and kinematics of orthopedic joints. Clinical applications. | ||
| 647 | KINEMATICS OF HUMAN BODY | 3 credits |
| Prerequisites: 4600:321 or equivalent, graduate standing in the College of Engineering or by permission. Analytical methods used to model and quantify human body motion. Three-dimensional kinematics, joint coordinate systems, functional anatomy, segment center of mass and joint centers. | ||
| 650 | CARDIOVASCULAR DYNAMICS | 3 credits |
| Analysis of blood pumping action, pressure/flow waveforms and transmission through circulation and blood rheology factors. Use of various modeling and measurement techniques. Clinical implications related to disease. | ||
| 651 | CARDIOVASCULAR DIAGNOSTIC TECH | 3 credits |
| Prerequisites: 3100:561, 562 or equivalent. Cardiovascular disease conditions, instrumentation and techniques (both invasive and noninvasive) used for diagnosis. Direct interaction with active clinical laboratories. | ||
| 652 | CARDIOVASCULR THERAPEUTIC TECH | 3 credits |
| Prerequisite: 651. Cardiovascular therapeutic devices and procedures for correction of congenital defects, value failure, heart and arterial bypass grafting and less invasive catheter-based procedures. | ||
| 653 | TRANSP PHEN BIOLOGY & MEDICINE | 3 credits |
| Prerequisites: 4200:321, 322 or 4600:310, 315 or equivalent. Basic definitions, cardiovascular mass and momentum transport, compartment modeling, mass transfer in physiological systems and artificial kidney and lung devices, Design optimization. Analysis of human thermal system. | ||
| 655 | REHABILITATION ENGINEERING | 3 credits |
| Prerequisites: graduate standing in engineering, mathematics, or science; or permission of the instructor. Devices for rehabilitation, interfacing the motor and/or sensory impaired, quantitative assessment techniques, prosthetics and orthotics, bedsore mechanics, emerging technologies. | ||
| 660 | BIOMATERIALS & LABORATORY | 4 credits |
| Corequisite: Biomaterials Laboratory. Material uses in biological applications. Effect of physiological environment and sterilization on materials. Controlled and uncontrolled degradation. Effect of materials on soft tissue, hard tissue and blood. Laboratory experiments using materials designed for biomedical use and demonstrations of biological/materials interactions. | ||
| 661 | ADVANCED BIOMATERIALS | 3 credits |
| Prerequisite: 660 or permission of instructor. The objective of this course is to provide the fundamental understanding of the host responses when exposed to various implantable devices and biomaterials. Methods for testing biocompatibility will be analyzed. | ||
| 663 | ARTIFICIAL ORGANS | 3 credits |
| Prerequisites: graduate standing in the College of Engineering or permission of instructor. Study of the rationale for the engineering and clinical aspects required for the design and variety of artificial organs, with emphasis on the artificial heart and artificial kidney. | ||
| 665 | BIOMATERIALS & TISSUE ENGR MTD | 3 credits |
| Prerequisite: 660; Corequisite: 661; or permission of the instructor. This course is design to equip students with knowledge and skills to evaluate biomaterials and to design scaffolds for tissue engineering. Analytical techniques include principles of microscopy, cell culture techniques, and biocompatibility testing. | ||
| 670 | MATH MODEL-BIOLOGY & MEDICINE | 3 credits |
| Prerequisites: graduate standing in engineering, mathematics, or physics; or permission of instructor. Modeling of pharmacokinetic, cardiovascular, neuromuscular, and immune systems, and artificial organ interactions. Deterministic and stochastic approaches. | ||
| 685 | MEDICAL DEVICE & ARTFCL ORGANS | 3 credits |
| Prerequisites: graduate standing in engineering, mathematics, or science; or permission of instructor. Design of medical devices and artificial organs, requirements, safety considerations, tissue constraints, optimization techniques, government regulations, and legal liability. | ||
| 697 | ST: BIOMEDICAL ENGINEERING | 1-4 credits |
| (May be repeated.) Specialized areas of study as defined by the instructor. | ||
| 698 | MASTERS RESEARCH | 1-6 credits |
| Prerequisite: Permission of advisor. (May be repeated.) Research on a suitable topic in biomedical engineering culminating in a master's thesis. | ||
| 699 | MASTERS THESIS-BIOMEDICAL ENG | 1-6 credits |
| Prerequisite: permission of advisor. (May be repeated) Supervised research in a specific area of biomedical engineering. | ||
| 730 | FAB & DESIGN MICROSENSORS | 3 credits |
| Sensing principles, fabrication, and engineering design of microsensors for diagnostic, monitoring, and analytical biomedical applications. | ||
| 735 | IMAGING DETECTORS & SENSORS | 3 credits |
| An introductory course designed to develop a deep knowledge of detector and sensing systems for Medical Imaging and Diagnostic Applications. | ||
| 898 | PRELIMINARY RESEARCH | 1-15 credits |
| (May be repeated) Prerequisite: Approval of the dissertation director. Preliminary investigations prior to the submission of a dissertation proposal to the Interdisciplinary Doctoral Committee. | ||
| 899 | DOCTORAL DISSERTATION | 1-15 credits |
| Prerequisite: acceptance of research proposal by the Interdisciplinary Doctoral Committee and approval of the dissertation director. (May be repeated) Original research by the doctoral student. | ||