ADVANCED BIOMATERIALS (Fa)
The objective of this course is to provide the fundamental understanding of the host responses when exposed to various implantable devices and biomaterials. Methods for testing biocompatibility will be analyzed.
ADVANCES IN DRUG AND GENE DELIVERY SYSTEMS (Fa)
This course will examine technological innovations for the delivery of drugs and genes. Methods of introducing drugs and genes into the body, modeling drug transport, and metabolic responses of cells and organs will be analyzed.
BIOFLUIDIC MICROTECHNOLOGIES (Sp)
Principles of single phase and multiphase microfluid mechanics, wetting and adhesion, flow control at the microscale, fabrication of biomedical microfluidic devices, applications of microfluidics in biomedicine, design of biomimetic functional units and organ on a chip, point-of-care diagnostic microfluidic devices.
BIOMATERIALS AND LABORATORY (Sp)
Material uses in biological applications. Effect of physiological environment and sterilization on materials. Controlled and uncontrolled degradation. Effect of materials on soft tissue, hard tissue and blood. Laboratory experiments using materials designed for biomedical use and demonstrations of biological/materials interactions.
BIOMATERIALS AND TISSUE ENGINEERING METHODS (Sp)
This course is designed to equip students with knowledge and skills to evaluate biomaterials and to design scaffolds for tissue engineering.
Analytical techniques include principles of microscopy, cell culture techniques, and biocompatibility testing.
BIOMEDICAL INSTRUMENTATION I (Fa)
Clinical instrumentation to measure and display physiologic and anatomic parameters. Basic concepts of instrumentation including design criteria and opera- tional analysis. Practical experience gained through the use of instrumented mammalian models.
BIOMEDICAL NANOTECHNOLOGY (Fa)
Engineering principles of nanotechnology as applied to the design of instrumentation, systems and techniques, aimed to explore biomolecules and biomaterials at the microscopic level, at one billionth of a meter.
BIOMEDICAL OPTICS (Sp)
Application of lightwave principles and optical fibers on the engineering design and development of instrumentation, techniques, and applications for medical diagnostic imaging, and treatment of disease.
Statistics and experimental design topics for the biomedical and biomedical engineering disciplines including: distributions, hypothesis testing and estimation, ANOVA, probit analysis and nonparametrics statistics.
DESIGN OF MEDICAL IMAGING SYSTEMS (Fa)
Physical principles and engineering design of medical imaging systems, with emphasis on digital radiography, computed tomography, nuclear medicine, ultrasound and magnetic resonance.
INTRODUCTION TO BONE BIOMECHANICS (Sp)
This course will introduce the student to mechanical aspects of bone through discussion of two main fields: Bone Biomechanics and Bone Mechanobiology. Efforts will be made to tie the two fields together to show the intricate and critical relationship between bone and mechanical loading. Class projects simulating actual clinical and basic science research will be required.
KINEMATICS OF THE HUMAN BODY (Sp)
Analytical methods used to model and quantify human body motion.
Three-dimensional kinematics, joint coordinate systems, functional anatomy, segment center of mass and joint centers.
MATHEMATICAL MODELING IN BIOLOGY AND MEDICINE (Sp)
Modeling of pharmacokinetic, cardiovascular, neuromuscular, and immune systems, and artificial organ interactions. Deterministic and stochastic approaches.
MECHANICS IN PHYSIOLOGY AND MEDICINE (Fa)
Blood rheology, mechanics of microcirculation, finite deformation theory, soft tissue mechanics, mechanics of blood and lymph circulation, kinetics and kinematics of orthopedic joints.
MECHANICS OF BIOLOGICAL TISSUES (Fa)
The structure, function and mechanical properties of major biological tissues are presented. Bone, articular cartilage, tendon, ligament and muscle will be addressed. Engineering concepts in statics, dynamics and mechanics of solids will be applied on biological tissues.
MEDICAL DEVICES AND ARTIFICIAL ORGANS (Fa)
Design of medical devices and artificial organs, requirements, safety considerations,tissue constraints, optimization techniques, government regulations, and legal liability.
MEDICAL IMAGING DEVICES (Fa)
Imaging modalities including radiation, magnetic resonance, and sound. The formation of images. Specific devices including computer tomography, magnetic resonance, ultrasound, gamma cameras and PET.
MEDICAL SIGNAL AND IMAGE PROCESSING (Fa)
Introduction to the basic problems associated with biological signal and image processing applications, and appropriate approaches to dealing with them.
TECHNIQUES IN BIOMATERIALS CHARACTERIZATION (Sp)
This course examines various required to evaluate and characterize biomaterials. Topics to cover range from NMR and SEM to AFM and rheology. Background, laboratory techniques, and analysis will be examined in the structure of the course.
TISSUE ENGINEERING (Fa)
The purpose of this course is to introduce students to tissue engineering. Tissue engineering aims to use of a combination of cells, biomaterials and suitable physio-chemical factors to improve or replace injured tissues. It is highly interdisciplinary and crosses numerous engineering and medical specialties. Topics include morphogenesis, tissue organization, stem cell, tissue engineering scaffolds and cell-matrix interaction. Examples of engineering tissues for replacing skin, cartilage, bone, nerve and blood vessel will be presented.
Supervised research in the specific area of biomedical engineering.
Approval of the dissertation director. Preliminary investigations prior to the submission of a dissertation proposal to the Interdisciplinary Doctoral Committee.
Original research by the doctoral student.