Dr. Hossein Tavana
Dr. Tavana received his PhD (2006) in Mechanical Engineering from University of Toronto where he studied interfacial tensions and contact angles of polymer films-fluid systems. His work led to a prestigious postdoctoral fellowship. Dr. Tavana joined the Biomedical Engineering department of the University of Michigan as a postdoctoral fellow in 2007 and developed novel microtechnologies that enable in vitro studies of cells in physiologic microenvironments. He joined the Biomedical Engineering department of the University of Akron in 2010 as an Assistant Professor. He currently directs the Biofluid Microtechnology laboratory.
Dr. Tavana’s research interest is to develop novel microtechnologies to enable studies of normal physiologic and pathologic events. His interdisciplinary research span several areas: (i) vascularized tissue engineering using a “bottom-up” cell printing approach, (ii) high-throughput screening of migration of cancer cells and testing the efficacy of migration inhibiting drugs, (iii) non-contact printing of multicellular embryonic stem cells differentiation niches, (iv) microfluidic tissue engineering, and (v) interfacial properties of biological systems. Dr. Tavana has published original research articles, review papers, and several book chapters in these areas. His publications have appeared in fundamental physical sciences journals as well as in high impact interdisciplinary journals such as Nature Materials, Nature Physics, Advanced Materials, and Lab on a Chip. His work has led to two US patents.
H. Tavana, B. Mosadegh, P. Zamankhan, S. Takayama, “Microprinted feeder cells guide embryonic stem cell fate”, Biotech. Bioeng. (in press).
H. Tavana, K. Kaylan, T. Bersano-Begey, K.E. Luker, G. D. Luker, S. Takayama, “Polymeric aqueous biphasic system rehydration facilitates high throughput cell exclusion patterning for cell migration studies”, Adv. Func. Mater. (in press).
H Tavana, P. Zamankhan, P.J. Christensen, J. B. Grotberg, S. Takayama, “Epithelium damage and protection during reopening of occluded airways in a physiologic microfluidic pulmonary airway model”, Biomed. Microdev. (in press).
H. Tavana, S. Takayama, “Aqueous biphasic microprinting approach to tissue engineering”, Biomicrofluidics 5 (2011) 013404—1013404-8.
B. Mosadegh, H. Tavana, S. C. Lesher-Perez, S. Takayama, “Patterned deactivation of oxidized polydimethylsiloxane surface for high-density fabrication of normally-closed microfluidic valves”, Lab Chip, 11, (2011) 738-742.
B. Mosadegh, M. Agarwal, H. Tavana, T. Bersano-Begey, Y. Torisawa, M. Morell, M. J. Wyatt, K. S. O'Shea, K. F. Barald, S. Takayama, “Uniform cell seeding and generation of overlapping gradient profiles in a multiplexed microchamber device with normally-closed valves”, Lab Chip, 10 (2010) 2959-2964.
H. Tavana, B. Mosadegh, S. Takayama, “Polymeric aqueous biphasic systems for non-contact cell printing on cells: Engineering heterocellular embryonic stem cell niches”, Adv. Mater., 22 (2010) 2628-2631.
H. Tavana, A. Jovic, B. Mosadegh, Q.Y. Lee, X. Liu, K.E. Luker, G.D. Luker, S.J. Weiss, S. Takayama, “Aqueous nanodrops in aqueous media: Genetic reagent patterning on living cells”, BIOforum Europe, 1-2, (2010) 17-20.
B. Mosadegh, C.-H. Kuo, Y.-C. Tung, Y. Torisawa, T. Bersano-Begey, H. Tavana, S. Takayama, “Integrated elastomeric components for autonomous control of microfluidic switching and oscillation” Nature Phys., 6 (2010) 433-437. Featured on Science Daily, Genetic engineering&Biotechnology News, University of Michigan News Service
H. Tavana, C.-H. Kuo, Q.Y. Lee, B. Mosadegh, D. Huh, P.J. Christensen, J.B. Grotberg, S. Takayama, “Dynamics of liquid plugs of buffer and surfactant solutions in a micro-engineered pulmonary airway model”, Langmuir, 26 (2010) 3744-3752.
H. Tavana, A. Jovic, B. Mosadegh, Q.Y. Lee, X. Liu, K.E. Luker, G.D. Luker, S.J. Weiss, S. Takayama, “Nanoliter liquid patterning in aqueous environments for spatially-defined reagent delivery to mammalian cells”, Nature Mater., 8 (2009) 736-741. Featured on Nature Materials, Science Daily, The Medical News, Life Sciences World, University of Michigan News Service
H. Tavana, D. Huh, J.B. Grotberg, S. Takayama, “Pulmonary airways on a chip: A new approach to study respiratory disorders”, BIOforum Europe, 7-8 (2008) 14-16.
S. Zschoche, R. David, H. Tavana, K. Pöschel, N. Petong, V. Dutschk, K. Grundke, A.W. Neumann, “Robustness of wetting and morphology of maleimide copolymer films to choice of solvent and annealing”, Colloids Surf. A: Physicochem. Eng. Aspects, 307 (2007) 53-61.
H. Tavana, D. Jehnichen, K. Grundke, M.L. Hair, A.W. Neumann, “Contact angle hysteresis on fluoropolymer surfaces”, Adv. Colloid Interface Sci., 134-135 (2007) 236-248.
H. Tavana, A.W. Neumann, “Recent progress in the determination of solid surface tensions from contact angles”, Adv. Colloid Interface Sci., 132 (2007) 1-32. (Top 25 Hottest Articles)
H. Tavana, A. Amirfazli, A.W. Neumann, “Fabrication of superhydrophobic surfaces of n-hexatriacontane”, Langmuir, 22 (2006) 5556-5559.
H. Tavana, A.W. Neumann, “On the question of rate-dependence of contact angles”, Colloids Surf. A: Physicochem. Eng. Aspects, 282-283 (2006) 256-262.
H. Tavana, M.L. Hair, A.W. Neumann, “Influence of electronic properties of naphthalene compounds on contact angles”, J. Phys. Chem. B, 110 (2006) 1294-1300.
H. Tavana, C. Yang, C.Y. Yip, D. Appelhans, S. Zschoche, K. Grundke, M.L. Hair, A.W. Neumann, “Stick-slip of the three-phase line in the measurements of dynamic contact angles”, Langmuir, 22 (2006) 628-636.
H. Tavana, D. Appelhans, R.-C. Zhuang, S. Zschoche, K. Grundke, M.L. Hair, A.W. Neumann, “Determination of accurate surface tensions of maleimide copolymers containing fluorinated side chain from contact angle measurements”, Colloid Polym. Sci., 291 (2005) 497-505.
H. Tavana, F. Simon, K. Grundke, D. Y. Kwok, M.L. Hair, A.W. Neumann, “Interpretation of contact angle measurements on two different fluropolymers for the determination of solid surface tension”, J. Colloid Interface Sci., 291 (2005) 497-506.
H. Tavana, N. Petong, A. Hennig, K. Grundke, A.W. Neumann, “Contact angles and coating film thickness”, J. Adhesion, 81 (2005) 29-39.
Bateni, S. Laughton, H. Tavana, S. Susnar, A. Amirfazli, A.W. Neumann, “Effect of electric fields on contact angle and surface tension of drops”, J. Colloid Interface Sci., 283 (2005) 215-222.
H. Tavana, C.N.C. Lam, K. Grundke, P. Friedel, D.Y. Kwok, M.L. Hair, A.W. Neumann, “Contact angle measurements with liquids consisting of bulky molecules”, J. Colloid Interface Sci., 279 (2004) 493-502.
H. Tavana, R. Gitiafroz, M.L. Hair, A.W. Neumann, “Determination of solid surface tension from contact angles: the role of shape and size of liquid molecules”, J. Adhesion, 80 (2004) 705-725. [PDF]
H. Tavana, A. Keshavarz, M. Ghassemi, “A new and energy efficient design for home refrigerator/freezers”, Environ. Cons. Des. Manufac. (ECDM), 10 (2001-02) 1-10.
S. Takayama, H. Tavana, A. Jovic, B. Mosadegh, “Solution microarrays”, application# 61094560.
S. Takayama, H. Tavana, A. Simon, “Dehydrated aqueous two phase systems”, Filed with the University of Michigan Technology Transfer Office# 4642.
Ph.D., University of Toronto, ON, Canada (2006); M.A.Sc., K.N. T. University of Technology, Tehran, Iran (1999); B.Sc., Tabriz University, Tabriz, Iran (1996)