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Extrusion Compounding and Applications in the Food, Medical Devices and Pharmaceutical Industries - 2 Day Course

Course Number: AP3555
Date: 10/13/2020 - 10/14/2020
Time: 8:00 AM - 4:00 PM
Location: Akron Polymer Training Center, Akron, OH 44325-5404, U.S.A.
Cost: $1,800.00 USD
Online Registration
CEU's: 1.6
Instructor: Mr. Christopher Paige

Course Overview

This two-day course will cover the single-screw and twin-screw compounding equipment and trouble-shooting issues, with compounding. There will be hands-on demonstrations and operation overviews on a single-screw extruder and a twin-screw extruder. The application of extrusion in the food, medical device and pharmaceutical industries will be discussed.

Instructor Biography:

Paige

Christopher (Chris) Paige holds a M. S. Degree in Plastics Engineering - 2005 (University of Massachusetts – Lowell) and a M.S. Degree in Polymer Chemistry – 1991 (University of Cincinnati). He is a member of Society of Plastics Engineers (SPE), American Chemical Society (ACS) and America Society of Materials (ASM) and has over 30 years’ experience, working in Industry. As a Laboratory Manager, at the University of Akron, Chris performed numerous hands-on plastics processing projects, for domestic and International corporate clients. He is a subject matter expert on Single Screw Extrusion, Twin Screw Extrusion, Blown Film Processing, 3-D Printing, Thermoforming and Injection Molding. Chris also trained Graduate and Undergraduate students on the hands-on operation of Large scale plastic processing equipment and characterization equipment (Thermal Analysis and mechanical Inston), while at the University of Akron.

Day1:

Single-Screw Equipment

  • Single-Screw (Drag-Flow) Operational Line Set-up
  • Single Rotating Screw Design
  • Preventive Maintenance
  • Safety Precautions

Twin-Screw Extrusion Equipment

  • Twin-Screw Operational Line Set-up
  • Screw Design (Co-rotating Screws verses Counter-Rotating Screws – Intermeshing or Non-Intermeshing)
  • Preventive Maintenance
  • Safety Precautions

Trouble -Shooting Extrusion Problems or Issues

  • What is Trouble-Shooting? – Note: Trouble- shooting is not Process Development or Process Scale-Up
  • Identification the problems that can occur with Single and Twin-Screw Extrusion Processing Equipment
  • Finding the Best Approach to resolving Processing Problems, or Issues

Hands-on Demonstration and Operation Overview of a Single-Screw Extruder

  • Single-Screw Extrusion Hands-on Demonstration
  • Single-Screw Extruder Operations Overview

Day 2:

Extrusion in the Food Industry

  • Food Extrusion Processing (Breakfast Cereal Products, Pet Foods and Pellet Products)
  • Post- Extrusion Processing (Cutting to size, Moisture Drying, Seasoning or Coating, to meet the Desired Flavor)
  • Packaging

Extrusion in the Medical Device Industry

  • FDA - 21 CFR Parts 210 and 211
  • Aluminum Extrusion, for Medical Device Product Production
  • Tube Extrusion, for Sterile Catheter Usage

Extrusion in the Pharmaceutical Industry

  • FDA – 21CFR Part 11, IQ/OQ/PQ – Validation, Process Analytical Technology (PAT)
  • Dispersion of Active Pharmaceuticals Ingredients (APIs) into Polymer Matrix, to form Solid Solutions
  • Compound Granulation of powders or Continuous Dosage Formulations

Hands-on Demonstration and Operation Overview of a Twin-Screw Extruder

  • Twin-Screw Extrusion Hands-on Demonstration
  • Twin-Screw Extruder Operation Overview